Rabbit Anti-Human GUK1 (pTyr53) Polyclonal: RPE
A phospho-specific peptide corresponding to residues surrounding Tyr53 of human GUK1 (AA50-56)
Human GUK1 (pTyr53)
Antibody's full description:
Rabbit Anti-Human GUK1 (pTyr53) Polyclonal
Antibody's other name:
GMK Antibody, GMP kinase Antibody, Guanylate kinase Antibody, GUK1 Antibody, KGUA_HUMAN Antibody
Antibody's recommended dilutions for use:
WB (1:250); optimal dilutions for assays should be determined by the user.
Antibody's purified from:
Peptide Affinity Purified
Recommended buffer for storage:
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 21.726 kDa.
Blue Ice or 4°C
Certificate of analysis:
A 1:250 dilution of SPC-992 was sufficient for detection of GUK1 (pTyr53) in 10 µg of human kidney lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
See included datasheet or contact our support service.
GUK1 (guanylate kinase 1), also known as GMK (GMP kinase), is a 197 amino acid protein that contains one guanylate kinase-like domain and belongs to the guanylate kinase family. Ubiquitously expressed, GUK1 exists as a monomer that catalyzes the ATP-dependent conversion of GMP to GDP, thereby playing an essential role in the recycling of GMP. Via its catalytic activity, GUK1 is thought to participate in regulating the supply of guanine nucleotides to signal transduction pathways. Overexpression of GUK1 is associated with pituitary adenocarcinomas, suggesting that GUK1 is involved in tumorigenesis.
Refer to PubMed
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
Representative figure link:
No Data Available
Country of production:
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.