Catalog number:
SPC-984D-RPE
Name:
Rabbit Anti-Human FRK (pTyr387) Polyclonal: RPE
Size:
100 µl
Supplier:
StressMark antibodies
Price:
394.00
Immunogen:
A phospho-specific peptide corresponding to residues surrounding Tyr387 of human FRK (AA384-390)
Antibody's target:
Human FRK (pTyr387)
Antibody's full description:
Rabbit Anti-Human FRK (pTyr387) Polyclonal
Antibody's category:
Polyclonal Antibodies
Antibody's other name:
Beta cell Src homology tyrosine kinase Antibody, FRK Antibody, BSK Antibody, BSK/IYK Antibody, C85044 Antibody, Frk fyn related kinase Antibody, FRK_HUMAN Antibody, FYN related kinase Antibody, GASK Antibody, Gastrointestinal associated kinase Antibody, GTK Antibody, Intestine tyrosine kinase Antibody, Nuclear tyrosine protein kinase RAK Antibody, Protein-tyrosine kinase 5 Antibody, PTK5 Antibody, RAK Antibody,Tyrosine protein kinase FRK Antibody
Verified applications:
WB, AM
Raised in:
Rabbit
Antibody's reactivity:
Human
Antibody's recommended dilutions for use:
WB (1:250); optimal dilutions for assays should be determined by the user.
Antibody's purified from:
Peptide Affinity Purified
Recommended buffer for storage:
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Antibody's concentration:
See included datasheet or contact our support service
Antibody's specificity:
Detects 58.254 kDa.
Storage recommendations:
-20°C
Shipping recommendations:
Blue Ice or 4°C
Certificate of analysis:
A 1:250 dilution of SPC-984 was sufficient for detection of FRK (pTyr387) in 10 µg of 293T cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Antibody in cell:
Cytoplasm, Nucleus
Tissue specificity:
Highly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon
Scientific context:
FRK is a protein-tyrosine kinase. It is involved in positive regulation of PTEN by increasing its stability and preventing degradation and negative regulation of cell proliferation. It may also have functions during G1 and S phase in the nucleus to suppress growth.
Bibliography:
Refer to PubMed
Released date:
29/Aug/2016
NCBI number:
NP_002022
Gene number:
2444
Protein number:
P42685
PubMed number:
Refer to PubMed
Tested applications:
To be tested
Tested reactivity:
To be tested
Antibody's datasheet:
Contact our support service to receive datasheet or other technical documentation.
Representative figure link:
No Data Available
Warning information:
Non-hazardous
Country of production:
Canada
Total weight (kg):
1.4
Net weight (g):
0.1
Stock availabilit:
In Stock
Description:
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Test:
StressMark antibodies supplies antibodies that are for research of human proteins.
Properties:
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Group:
Polyclonals and antibodies
About:
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Latin name:
Oryctolagus cuniculus