Catalog number:
SPC-1045D-APC
Name:
Rabbit Anti-Human PAK5 (pSer602) Polyclonal: APC
Size:
100 µl
Supplier:
StressMark antibodies
Price:
396.00
Immunogen:
A phospho-specific peptide corresponding to residues surrounding Ser602 of human PAK5 (AA599-605)
Antibody's target:
Human PAK5 (pSer602)
Antibody's full description:
Rabbit Anti-Human PAK5 (pSer602) Polyclonal
Antibody's category:
Polyclonal Antibodies
Antibody's other name:
PAK 5 Antibody, PAK 7 Antibody, PAK-5 Antibody, PAK-7 Antibody, PAK5 Antibody, PAK7 Antibody, PAK7_HUMAN Antibody, Protein kinase PAK5 Antibody, Serine/threonine protein kinase PAK 7 Antibody, Serine/threonine-protein kinase PAK 7 Antibody, EC 2.7.11.1 Antibody, KIAA1264 Antibody, MGC26232 Antibody, p21 activated kinase 7 Antibody, p21 protein (Cdc42/Rac)-activated kinase 7 Antibody, p21(CDKN1A) activated kinase 7 Antibody, p21-activated kinase 5 Antibody, p21-activated kinase 7 Antibody
Verified applications:
WB, AM
Raised in:
Rabbit
Antibody's reactivity:
Human
Antibody's recommended dilutions for use:
WB (1:250); optimal dilutions for assays should be determined by the user.
Antibody's purified from:
Peptide Affinity Purified
Recommended buffer for storage:
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Antibody's concentration:
See included datasheet or contact our support service
Antibody's specificity:
Detects 80.745 kDa.
Storage recommendations:
-20°C
Shipping recommendations:
Blue Ice or 4°C
Certificate of analysis:
A 1:250 dilution of SPC-1045 was sufficient for detection of PAK5 (pSer602) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Antibody in cell:
Mitochondrion, Cytoplasm, Nucleus
Tissue specificity:
Highly expressed in the brain.
Scientific context:
PAK7 is a serine/theonine protein kinase activated by Rac/cdc42 and thus involved in regulation of cytoskeleton, cell surival and proliferation through RAF1 signalling. It phosphosphorylates BAD and prevents apoptosis. It is also involved in microtuble stablization, neurite outgrowth and development. It can destablize F-acting networks and eliminate stress fibres and focal adhesions. Pak7 expression provides a survival and could contribute to oncogenesis in this way.
Bibliography:
Refer to PubMed
Released date:
29/Aug/2016
NCBI number:
NP_065074
Gene number:
57144
Protein number:
Q9P286
PubMed number:
Refer to PubMed
Tested applications:
To be tested
Tested reactivity:
To be tested
Antibody's datasheet:
Contact our support service to receive datasheet or other technical documentation.
Representative figure link:
No Data Available
Warning information:
Non-hazardous
Country of production:
Canada
Total weight (kg):
1.4
Net weight (g):
0.1
Stock availabilit:
In Stock
Description:
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Test:
StressMark antibodies supplies antibodies that are for research of human proteins.
Properties:
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Group:
Polyclonals and antibodies
About:
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Latin name:
Oryctolagus cuniculus