Catalog number:
SPC-1001D-APC
Name:
Rabbit Anti-Human JAK3 (pTyr980+pTyr981) Polyclonal: APC
Size:
100 µl
Supplier:
StressMark antibodies
Price:
396.00
Immunogen:
A phospho-specific peptide corresponding to residues surrounding Tyr980 and Tyr981 of human JAK3 (AA977-985)
Antibody's target:
Human JAK3 (pTyr980+pTyr981)
Antibody's full description:
Rabbit Anti-Human JAK3 (pTyr980+pTyr981) Polyclonal
Antibody's category:
Polyclonal Antibodies
Antibody's other name:
EC 2.7.10.2 Antibody, JAK 3 Antibody, JAK L Antibody, JAK3 HUMAN Antibody, Janus kinase 3 (a protein tyrosine kinase, leukocyte) Antibody, Janus kinase 3 Antibody, L JAK Antibody, Leukocyte janus kinase Antibody, Protein tyrosine kinase leukocyte Antibody, Tyrosine protein kinase JAK3 Antibody
Verified applications:
WB, AM
Raised in:
Rabbit
Antibody's reactivity:
Human
Antibody's recommended dilutions for use:
WB (1:250); optimal dilutions for assays should be determined by the user.
Antibody's purified from:
Peptide Affinity Purified
Recommended buffer for storage:
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Antibody's concentration:
See included datasheet or contact our support service
Antibody's specificity:
Detects 125.016 kDa.
Storage recommendations:
-20°C
Shipping recommendations:
Blue Ice or 4°C
Certificate of analysis:
A 1:250 dilution of SPC-1001 was sufficient for detection of JAK3 (pTyr980+pTyr981) in 10 µg of Jurkat cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Antibody in cell:
Endomembrane system, Nucleus
Tissue specificity:
Expressed in blood, bone marrow and lymph node.
Scientific context:
JAK3 is a protein-tyrosine kinase and it is involved in cytokine receptor-mediated intracellular signal transduction, including activation of an oncoprotein, PI3K. Mutations in this gene have been found in blood, mouth, and ovarian cancers.
Bibliography:
Refer to PubMed
Released date:
29/Aug/2016
NCBI number:
NP_000206
Gene number:
3718
Protein number:
P52333
PubMed number:
Refer to PubMed
Tested applications:
To be tested
Tested reactivity:
To be tested
Antibody's datasheet:
Contact our support service to receive datasheet or other technical documentation.
Representative figure link:
No Data Available
Warning information:
Non-hazardous
Country of production:
Canada
Total weight (kg):
1.4
Net weight (g):
0.1
Stock availabilit:
In Stock
Description:
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Test:
StressMark antibodies supplies antibodies that are for research of human proteins.
Properties:
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Group:
Polyclonals and antibodies
About:
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Latin name:
Oryctolagus cuniculus